Medications for morning sickness | Neeva Baby

Morning sickness is defined as nausea and vomiting during pregnancy. It affects more than 75% of pregnant women and tends to go away on its own after the first trimester. However, some women may experience morning sickness throughout their pregnancy, which is when it gets difficult to tolerate and needs treatment.

It is believed that taking Vitamin B6 and Unisom during pregnancy can treat these symptoms. Still, you must be careful using these medications. 


Morning Sickness and B6 and Unisom in Pregnancy

Morning sickness is considered one of the first signs of pregnancy that begins around the sixth week. It is believed that morning sickness occurs due to fluctuations in hormone levels during this period.

Vitamin B6 is good for mothers with mild to moderate nausea. Antihistamines are also used to treat nausea and vomiting in pregnancy. Your doctor may prescribe doxylamine - an antihistamine available as a sleeping pill under the brand “Unisom Nighttime SleepAids.” It is easy to mistake Unisom Nighttime Sleep-Aid with Maximum Strength Unisom SleepGels, as they are two completely different medications.

Unisom can make you sleepy, so do not take it while driving. Vitamin B6 and Unisom are often used in combination to treat morning sickness. The FDA has approved a combination of vitamin B6 and doxylamine (Unisom) to treat nausea and vomiting during pregnancy. Your doctor may prescribe a prescription for this medicine or a variety of other medications such as Ondansetron (Zofran), Trimethobenzamide (Tebamide), or Promethazine (Phenergan antihistamine).


Home Remedies to Treat Morning Sickness

For most pregnant women, morning sickness stops in the twelfth or thirteenth week, but it lasts until the end of pregnancy for many. To manage and control morning sickness, there are certain do's and don'ts that you need to follow:

  • Eat smaller meals but eat more often
  • Drink plenty of fluids, especially water
  • Drink water about half an hour before and after meals; do not drink water during meals.
  • Continue to drink fluids throughout the day to stay hydrated; vomiting can cause you to lose a lot of fluids, which can be dangerous for you and your baby.
  • Eat whenever you want, and don’t look for a predetermined time 
  • Find someone who can prepare your meals for you, because for many women, the smell of cooking makes nausea worse
  • Open the windows and turn on the fans to minimize unpleasant odors, especially when cooking
  • Rest as much as you can
  • Avoid heat outside, as it can make nausea worse
  • Eat watermelon, drink ginger or lemonade drinks, or smell lemon to reduce nausea.
  • Exercise regularly
  • Eat some salt chips before meals to calm the stomach
  • Avoid lying down after eating
  • Avoid skipping any meals
  • Do not eat spicy food


Treating Morning Sickness by B6 and Unisom during Pregnancy

If the home remedies do not work for you, you can take certain medications to treat it. While there are many treatments and supplements to treat morning sickness, you need to ensure they are safe to take during pregnancy. Many women find that taking vitamin B6 and Unisom simultaneously can help reduce their nausea symptoms. However, vitamin B6 and Unisom are unlikely to reduce vomiting in pregnancy.

To treat morning sickness, it is recommended that you take 10 to 25 mg of both mediations every eight hours. Some of the side effects of Vitamin B6 and Unisom during pregnancy include:

  • Fatigue
  • Headache
  • Paresthesia (a prickling or burning sensation in hands, arms, legs, etc.)

Unisom is sold under the Unisom SleepTabs brand and is available over-the-counter in most pharmacies. You should take about 10 to 25 mg of vitamin B6 at least 2 to 3 times a day, and to treat morning sickness, take 25 mg Unisom just once a night before going to bed.


Dosage and Side Effects of taking Unisom in Pregnancy

Depending on your situation, your doctor may change the dose recommendations. Also, do not take any medication without consulting your doctor. Always double-check all active ingredients in the medication before starting any of them, especially when pregnant.

Some randomized clinical trials have shown that this combination therapy can help reduce nausea and vomiting in some women. However, treatment is not without side effects. Some common side effects of taking Unisom during pregnancy include:

  • Drowsiness
  • Headache
  • Dry mouth
  • Constipation or diarrhea
  • Rash 
  • Stomachache
  • Upset stomach 
  • Nervousness 

If these symptoms do not go away or worsen after a while, you should visit a doctor. Apart from these side effects, certain serious side effects may be due to taking Unisom for morning sickness, which include:

  • Irregular or rapid heartbeat
  • Urinary retention or painful urination
  • Confusion
  • Shortness of breath
  • Convulsions
  • Blurred vision
  • Dilated pupils or other vision problems

Suppose you experience any of these side effects listed above. In that case, you should stop taking both Vitamin B6 and Unisom in pregnancy immediately and see a doctor as soon as possible.


Is Unisom Safe during Pregnancy?

You can also take Unisom tablets twice a day. Unisom is an over-the-counter sleep medication safe for pregnancy and can help treat nausea. (Make sure the active ingredient is doxylamine succinate.)

But you may also ask, “can I take Unisom every night?” The short answer is no. Unisom is intended as a temporary sleep aid and should not be used for more than two weeks. If you need constant help falling asleep, talk to your healthcare provider and find another way.


What are Unisom Pregnancy Birth Defects?

There is a slight chance that taking Doxylamine (Unisom) can lead to some birth defects. These birth defects include cleft lip and palate, pyloric stenosis, left heart hypoplastic syndrome (HLHS), spina bifida, and neural tube defects.



While using this combination therapy with Unisom and Vitamin B6 is effective in most cases of morning sickness, you will not find any relief if you find that you have been unable to get rid of your morning sickness no matter what medication you are taking. Well, it could mean that you have severe pregnancy vomiting. In this case, it is best to see your doctor as soon as possible to diagnose your condition and start the proper prescription medication to reduce your symptoms.

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